New drug 'functionally cures' many hepatitis B virus infections

218 points · 39 comments on HN · read original →

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What commenters are saying

The thread centers on whether treated patients remain contagious. Commenters note the trial enrolled non-cirrhotic patients already on existing antivirals, limiting generalizability to the 1.1 million annual HBV deaths. Key debate: whether undetectable viral load means non-transmissible (citing HIV's U=U framework) versus uncertainty around latent virus and temporary suppression. One commenter notes blood-based PCR testing's high sensitivity compared to coronavirus detection. Secondary discussion questions why HSV and HPV deserve more focus despite HBV's 300 million existing infections and carcinogenicity.